The registrant/filer may apply the seven types of evidence outlined in the Guidelines for the Use of Cosmetic Ingredient Data to conduct safety assessments for most ingredients listed in the Inventory of Existing Cosmetic Ingredients in China (IECIC) .
For a small number of ingredients where the above evidence types cannot be applied, the registrant/filer should follow the requirements of the Technical Guidelines for Cosmetic Safety Assessment to determine potential health hazard effects, including phototoxicity and photoallergenicity, based on factors such as product usage and exposure routes.
If a comprehensive analysis or testing of the ingredient’s structural characteristics demonstrates that it does not have UV absorption properties or that it has no potential for outdoor strong UV exposure (e.g., ingredients used in rinse-off products or cosmetics intended for nighttime use), the assessment of skin phototoxicity and photoallergenicity may be exempted.