Inventory of Existing Cosmetic Ingredients in China (IECIC) is an official list that catalogs all cosmetic ingredients previously used in China which can be a reference to check if belong to a new cosmetic ingredient in China.
On April 30, 2021, China's National Medical Products Administration (NMPA) released the "Inventory of Existing Cosmetic Ingredients (2021 Edition)" which has been effective since May 1, 2021. On June 24, 2025, China’s NMPA further standardized the management of cosmetic ingredients by dividing the Inventory of Existing Cosmetic Ingredients in China (IECIC) into two lists: IECIC I and IECIC II.
IECIC II comprises new cosmetic ingredients that, having been registered or filed in China and completed the safety monitoring period, satisfy the conditions for inclusion in the IECIC. IECIC II now includes two new cosmetic ingredients “ACETYLNEURAMINIC ACID” and “BETA-ALANYL HYDROXYPROLYLDIAMINOBUTYROYL BENZYLAMIDE” of which have completed the three-year post-market safety monitoring period following notification. Upon evaluation, they were found to comply with applicable regulatory requirements.
- For ingredients included in IECIC II that are also listed as prohibited, restricted, or permitted cosmetic ingredients, registrants and filers shall use them in accordance with the mandatory national standards and technical specifications.
- The usage purposes and safety limits of ingredients included in IECIC II are derived from research materials provided by registrants or notifiers of new cosmetic ingredients.
- If the source, manufacturing process, or other aspects of an ingredient materially affect its substance or safety, relevant details-such as species, plant part used, preparation method, strain origin, or cell source-should be specified in the remarks section as applicable.
Regulatory Implications of the IECIC
The importance of the IECIC lies in regulating the range of ingredients that can be used in cosmetics, helping to ensure the safety and compliance of cosmetics. In the Chinese market, cosmetic companies need to closely monitor the updates and changes to the IECIC to ensure that the ingredients they use comply with the inventory's requirements. Additionally, for new ingredients not included in the IECIC, companies must undergo the necessary application and approval processes to ensure product compliance.
How to Search the IECIC II
- Click here to search the IECIC II on GlobalCosIng.
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