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Filing of New Cosmetic Ingredient in China | Six Ingredients Successfully Filed in October

Oct 15, 2025
China
Cosmetic Ingredient
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Based on data retrieved from China’s National Medical Products Administration (NMPA), six new cosmetic ingredients have successfully been filed between October 1-12, 2025. Detailed information is provided in the table below. At present, the associated technical specifications have not been made public, and the ingredient has not yet entered the post-filing monitoring period. As of now, a total of 123 new cosmetic ingredients have been successfully filed in 2025.

Filing Date

Standard

Chinese Name

English Name

(for reference)

Filing Number

Filer

Filer
Location

2025/10/9

沙枣(ELAEAGNUS ANGUSTIFOLIA)树胶提取物

Elaeagnus Angustifolia Gum Extract

GZYBZ 20250119

Yili Zisuli Ren Biotechnology Co., Ltd.

China Domestic

2025/10/10

乙酰基酪氨酰环D-谷氨酰三肽-110酰胺

Acetyl Tyrosyl-Cyclo(D-Glutamyl-Glutamyl) Tripeptide-110 Amide

GZYBZ 20250120

Harbin FuErJia Technology Co., Ltd.

China Domestic

2025/10/10

异山梨醇二辛酸酯

Isosorbide Discaprylate

GZYBZ 20250121

Shanghai Huarun Industrial Co., Ltd.

China Domestic

2025/10/10

羧甲基纤维素-多聚赖氨酸共聚物

Carboxymethyl Cellulose-Polylysine Copolymer

GZYBZ 20250122

Shenzhen Dingsheng Biotechnology Co., Ltd.

China Domestic

2025/10/11

癸酰基丝氨酸甲酯

Caproyl Serine Methyl Ester

GZYBZ 20250123

Korea New Drug Co., Ltd.

Korea

2025/10/11

甘草查尔酮A

Licochalcone A

GZYBZ 20250124

Beijing Nuobote Biotechnology Co., Ltd.

China Domestic

Note: The English names of the companies listed above are for reference only. Please refer to the official registered or commonly used names for formal use.

Interpretation of Selected New Cosmetic Ingredients

According to research, Elaeagnus angustifolia L. is native to Western Asia and is now mainly distributed in Northwest China, northern North China, and western Northeast China. It is also found in Arab countries.

Elaeagnus angustifolia has high medicinal and edible value. The fruit is sour, slightly sweet, and cool in nature; the bark is sour, slightly bitter, and cool; the stems and roots contain alkaloids; the leaves and dried branches also contain catechin and epicatechin. The fruit has the effect of strengthening the spleen and stopping diarrhea, and is used for indigestion and related symptoms; the bark has the functions of clearing heat, cooling the blood, astringing, and relieving pain, and is used for chronic bronchitis, stomach pain, enteritis, and leucorrhea, and externally for treating burns and stopping bleeding.

When the stems and branches of the Elaeagnus angustifolia tree are injured, they exude a transparent brownish gum, which, after drying, forms Elaeagnus angustifolia gum – a high-quality natural resource. In Xinjiang folk tradition, Elaeagnus angustifolia gum has long been used for hair care. Its recent successful registration marks the official entry of this traditional resource into the field of modern cosmetic ingredients.

Isosorbide dicaprylate (CAS No. 64896-70-4), with the molecular formula C22H38O6, is a compound formed through the esterification of isosorbide (a derivative of naturally occurring sugar alcohol sorbitol) and caprylic acid. The ester bonds and hydroxyl groups in its molecular structure give it excellent polarity and skin affinity, allowing it to mimic natural sebum. It forms a breathable protective film on the skin surface, effectively locking in moisture and reducing water loss while avoiding pore blockage, thereby providing long-lasting hydration. (Source: Shanghai Huarun Industrial Co., Ltd. Official WeChat Account)

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The CIRS cosmetic team is dedicated to ensuring that cosmetic products meet stringent global regulatory standards. It can provide one-stop services covering the whole life-cycle of a personal care product, which includes cosmetic ingredient development, physical/chemical tests, toxicological tests (in vivo & in vitro), efficacy studies (in vivo & in vitro), ingredient registration, and product registration.

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