To help stakeholders stay informed of the latest developments and gain insights into market trends, this article provides a systematic review and in-depth analysis of the cosmetic ingredient filings published by China’s National Medical Products Administration (NMPA) in August 2025. The report mainly covers the number of new ingredient filings during the month, basic information about the filing enterprises, the regional distribution of domestic filers, ingredients that have been filed multiple times, and interpretations of selected ingredients. It aims to offer valuable data support and information references for the cosmetics industry.
I. Number of New Cosmetic Ingredient Filings in China – August 2025
According to data from the NMPA, a total of 14 new cosmetic ingredients were successfully filed in August 2025. As of now, the relevant technical specifications for these ingredients have not yet been disclosed, and none of them have entered the post-filing monitoring period. For detailed information, please refer to Table 1 below. As of August 31, 2025, a total of 105 new cosmetic ingredients have been filed in China in 2025.
Table 1
Note: The English names of the companies listed above are for reference only. Please refer to the official registered or commonly used names for formal use.
II. Overview of Enterprises Filing for New Cosmetic Ingredients
(I) Domestic and Overseas Distribution of Enterprises Filing for New Ingredients
As shown in Figure 1 below, among the 14 new cosmetic ingredients that obtained filing numbers in August 2025, 13 were filed by Chinese domestic enterprises, accounting for approximately 92.86%, while one was filed by an overseas enterprise, accounting for approximately 7.14%. The number of domestic filers significantly exceeds that of overseas filers.
Figure 1
(II) Domestic Enterprises
Based on the analysis of filing data for new cosmetic ingredients, all 13 approved ingredients were individually filed by 13 separate enterprises.
(III) Overseas Enterprises
Based on the analysis of filing data for new cosmetic ingredients, one of the ingredients was filed by a France-based company, Galenic Cosmetics Laboratory, as detailed in Table 2.
Table 2
III. Distribution of Domestic Enterprises Filing for New Cosmetic Ingredients by Province
According to the analysis of new ingredient filing data, a total of 13 new cosmetic ingredients were filed by domestic enterprises in China, involving 13 companies across 9 provincial-level regions (special administrative region). These regions include Guangdong, Beijing, Zhejiang, Anhui, Hunan, Shandong, Shanghai, Sichuan, and Hong Kong.
As illustrated in Figure 2, among all provinces where domestic filers are located, Guangdong Province recorded the highest number of new ingredient filings, with a total of 3. This accounts for approximately 23% of all new ingredient filings by domestic enterprises in August 2025.
Figure 2
IV. Frequently Filed New Cosmetic Ingredients
Based on the statistics presented in Table 3, among the 14 cosmetic ingredients that have obtained registration numbers, Urolithin A (尿石素A) was also previously filed in 2023.
Table 3
V. Interpretation of Selected Ingredients
According to available data, diacylglycerol (DAG) primarily consists of two structural isomers: 1,3-diacylglycerol and 1,2-diacylglycerol. Due to the presence of two long-chain fatty acids and one hydroxyl group in its molecular structure, diacylglycerol exhibits strong lipophilicity and a certain degree of hydrophilicity. At present, diacylglycerol is widely used in various fields such as food, pharmaceuticals, and chemical industries. In 2009, the former Ministry of Health of China approved diacylglycerol oil as a novel food ingredient (Announcement No. 18 of 2009).
Paeonia suffruticosa, commonly known as tree peony, is a deciduous shrub species belonging to the Paeoniaceae family and the Paeonia genus. In China, Luoyang in Henan Province and Heze in Shandong Province are the two largest cultivation bases for tree peony.
Paeonia suffruticosa Callus Extract is derived through advanced plant callus culture technology, which has enabled the breakthrough establishment of a long-term wild tree peony cell culture system, preserving the unique bioactive advantages of wild peony components. Furthermore, in vitro cellular studies have demonstrated that the active constituents in Paeonia suffruticosa callus extract exhibit anti-photoaging properties, elucidating its underlying mechanisms of action.
6'-Sialyllactose Sodium Salt (CAS No. 157574-76-0) is a carbohydrate compound classified as a derivative of sialic acid. It holds promising potential in areas such as cell recognition, immune regulation, and gut health.
Paeonia emodi is a perennial herbaceous plant belonging to the family Ranunculaceae and the genus Paeonia. It is distributed in southern Tibet (Gyirong), China, as well as in Nepal and northern India, typically growing on mountain slopes at an altitude of approximately 2,350 meters. Paeonia emodi seed oil is obtained through the extraction and refinement of the mature seeds of the plant.
Annona squamosa L., a deciduous small tree of the family Annonaceae and the genus Annona, is native to tropical America. It was introduced into China approximately 300 years ago and is now widely cultivated in tropical regions, particularly in southern tropical cities of China such as Hainan, Guangdong, and Guangxi. The fruit of Annona squamosa is aromatic and sweet, suitable for fresh consumption, and rich in nutrients such as proteins, carbohydrates, and fats, offering high edible and economic value. Its seeds contain oil; the bark fiber can be used in papermaking; and the root bark and fruit possess certain medicinal properties, traditionally used in the treatment of dysentery and spinal disorders.
Dihydro-resveratrol (CAS No. 58436-28-5) is an organic compound with the chemical formula C14H14O3. It belongs to the class of dihydrostilbenoids and has been identified in wine.
Baicalin is a flavonoid compound extracted and isolated from the dried roots of Scutellaria baicalensis Georgi, a dicotyledonous plant of the family Lamiaceae. At room temperature, it appears as a pale yellow powder with a bitter taste. Studies have shown that baicalin possesses antibacterial, diuretic, and anti-inflammatory properties, and it is widely used in traditional Chinese medicine as well as in modern pharmaceutical research and development.
Dendrobium devonianum Paxton is an epiphytic herbaceous plant belonging to the genus Dendrobium in the family Orchidaceae. In China, it is mainly distributed in Guangxi, Yunnan, Guizhou, and southeastern Tibet, and is also found in countries such as Thailand, Laos, and Vietnam. Dendrobium devonianum is classified as a nationally protected Class II wild plant in China, and is listed as Endangered (EN) on the IUCN Red List of Threatened Species.
According to the Catalogue of Traditional Chinese Medicinal Resources in Yunnan and the Materia Medica of Yunnan, this species possesses significant medicinal value. In traditional Chinese medicine (TCM), it is believed to have the effects of clearing heat, nourishing yin, promoting fluid production, and benefiting the stomach, making it an important medicinal plant resource in China.
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About CIRS
The CIRS cosmetic team is dedicated to ensuring that cosmetic products meet stringent global regulatory standards. It can provide one-stop services covering the whole life-cycle of a personal care product, which includes cosmetic ingredient development, physical/chemical tests, toxicological tests (in vivo & in vitro), efficacy studies (in vivo & in vitro), ingredient registration, and product registration.
Cosmetic services in China:
- China Cosmetic Registration and Filing;
- China New Cosmetic Ingredient Registration and Filing;
- China Cosmetic Ingredient Quality and Safety Information Code Application (NMPA Code);
- China Cosmetics Safety and Efficacy Test;
- China Cosmetic Safety Assessment Report;
- China Toothpaste Filing;
- China Disinfectant Notification;
- China Cosmetic Formula/Label/Claim Review; and
- Customs Clearance
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